Formulation and Evaluation of Catfish ( Calias Sp ) Albumin Extract Ointment with Variations of Basis

Authors

  • Erik Risnawan STIKes Muhammadiyah Ciamis
  • Davit Nugraha STIKes Muhammadiyah Ciamis

DOI:

https://doi.org/10.52221/dwj.v1i1.220

Keywords:

Vaseline Flavum, Ointment.

Abstract

Catfish (Clarias sp) contains albumin which is an important protein needed by the human body, especially in the process of healing diseases. Giving this catfish extract functions as a nutrient, it is hoped that this nutrition can improve nutrition, increase the immune system and speed up the wound healing process or post surgery. This research is an experimental research, in which the albumin ointment formulation of catfish (clarias sp) extract was carried out, with variations of vaselin flavum and adeps lanae ointment bases in three formulations namely formulation 1, formulation 2 and formulation 3. The results of catfish extract (clarias sp) were then formulated in the form of an ointment. Then an evaluation of physical properties was carried out including organoleptic evaluation, homogeneity test, spreadability test, adhesion test, pH test. The results showed that the albumin extract ointment for catfish (Clarias sp) with variations in ointment base made a difference to the evaluation of albumin extract for catfish (Clarias sp) which included organoleptic tests (soft shape, white to yellow), homogeneity test (has round particles, irregular, no foreign particles), spreadability test (FI, 5.16cm: FII, 5.23cm: FIII, 5.06cm), adhesion test (FI, 3.19 seconds, FII 2.27 seconds, FIII 3.24 seconds), pH test (FI 6, FII 6, FIII 6). The conclusion that the vaseline flavum ointment combined with adeps lanae from catfish albumin extract meets the quality consists of an evaluation. homogeneity test, organoleptic test, adhesion test, spreadability test and pH test.

References

Garner, B. C. (2011). Albumin. In Clinical Veterinary Advisor: The Horse. https://doi.org/10.1097/01.ccm.0000199046.64077.bf

Harianti. (2011). Ikan Gabus (Channa striata) dan Berbagai Manfaat Albumin yang Terkandung di Dalamnya. Jurnal Balik Diwa.

Kartika, R. W., Bedah, B., Paru, J., & Luka, A. P. (2015). Perawatan Luka Kronis dengan Modern Dressing. Perawatan Luka Kronis Dengan Modern Dressing.

[Harianti, "Snakefish (Channa striata) and the Various Benefits of Albumin Contained in It," J. Balik Diwa , 2011.

RW Kartika, B. Bedah, J. Lung, and AP Wound, "Chronic Wound Care with Modern Dressing," Chronic Wound Treatment with Mod. dresses. , 2015.

IA Suryadi, A. Asmarajaya, and S. Maliawan, "The Process of Healing and Handling Wounds," Surgery , 2012.

J. Anggowarsito, "Burns from a Dermatological Point of View," J. WIDYA Med. , 2014, doi: 10.33508/jwm.v2i2.852.

Listiana, L., Wahlanto, P., Ramadhani, S. S., & Ismail, R. (2022). Penetapan Kadar Tanin Dalam Daun Mangkokan (Nothopanax scutellarium Merr) Perasan Dan Rebusan Dengan Spektrofotometer UV-Vis. Pharmacy Genius, 1(1), 62–73.

Tutik Rahayuningsih, "Management of Burns (Combustio)," Profession , 2012.

LA Purwaningsih and EM Rosa, "Response to physiological and psychological adaptation of burn patients given a combination of alternative moisture balance dressings and seft therapy at Dr. Sardjito Yogyakarta," Majapahit Hospital , 2016, doi: 10.2527/jas2012-5761.

D. Rosalina, "A Feasibility Analysis of Catfish Cultivation in Tarpaulin Ponds in Namang Village, Central Bangka Regency," Maspari J. , 2015, doi: 10.5376/ija.2014.04.0004.

SO Madyowati, "POTENTIAL ABOUT PLANKTON IN CATFISH CULTIVATION (Clarias gariepinus) tarpaulin ponds with SAMAN'S FISH PROBIOTIC TECHNOLOGY," J. TECHNO-FISH , 2017.

JHM Dian K. Dewi, "ANALYSIS OF CATFISH CULTURE PRODUCTION (Clarias gariepinus): A FUNCTIONAL APPROACH TO COBB DOUGLAS PRODUCTION," J. Perikan. (J. Fish. Sci.) , 2015.

MW Fitriadi et al. , "THE PRODUCTION PERFORMANCE OF DUMBO CATFISH (Clarias gariepinus) KEPT WITH CONVENTIONAL AND AQUAPONIC BIOFILTER SYSTEMS," J. Aquac. Manag. Technol. , 2015.

[Z. Abidin, M. Junaidi, . P., N. Cokrowati, and S. Yuniarti, "Growth and consumption of feed for catfish (Clarias sp.) which is fed with feed made from local raw materials," DEPIK , 2015.

D. Rachmawati, I. Samidjan, and H. Setyono, "Water Quality Management of Sangkuriang Catfish (Clarias gariepinus) Cultivation Media with Probiotic Techniques in Tarpaulin Ponds in Reksosari Vocational Village, Suruh District, Semarang Regency," Pena Aquatika , 2015.

Fitria, V., Ismail, R., & Nugraha, D. (2017). Uji Aktivitas Mukolitik Infusa Daun Karuk (Piper Sarmentosumroxb. Ex. Hunter) Pada Mukus Usus Sapi Secara In VitrO. DII Farmasi Stikes Muhammadiyah: Ciamis, 9-11.

NI Pramudita and H. Yuliansyah, "MOSELE: APPLICATIONS FOR MOBILE LEARNING CATFISH CULTIVATION OF ANDROID-BASED TARP SYSTEM," InfoTekJar (Journal of Nas. Inform. and Teknol. Network) , 2018.

“MORPHOLOGY AS AN APPROACH TO UNDERSTANDING THE CITY,” J. Perenc. Wil. and UNISBA City , 2007.

DY Maulid et al. , "DNA Barcoding for Authentication of Mackerel Products (Scomberomorus sp)," J. Aquatika , 2015.

S. Kaya and AR Tekin, "Effect of ointment content on the rheological characteristics of a typical ice-cream mix," J. Food Eng. , 2001.

D. . DM Radji, Textbook of Microbiology: A Pharmacy and Medical Student Guide . 2011.

RI Ministry of Health, Indonesian Pharmacopoeia, 4th edition . 1995.

MG Traber, “Vitamin E,” in Encyclopedia of Dietary Supplements , 2004.

F. Kratz, “Albumin as a drug carrier: Design of prodrugs, drug conjugates and nanoparticles,” J. Control. Release , 2008.

GR Pongsipulung, PVY Yamlean, and Y. Banne, "Formulation and Testing of Ambon Banana Weevil Extract Ointment (Musa paradisiaca var. sapientum L.) Against Open Wounds on the Skin of Wistar Strain Male White Rats (Rattus norvegicus)," Pharmacon , 2012.

Yuliani, W., & Ismail, R. (2023). Uji Aktivitas Antijamur Fungi Endofit Tanaman Sarang Semut (Myrmecodia pendans) Terhadap Jamur Candida albicans. Pharmacy Genius, 2(1), 31–42.

Yusuf, A. L., Nugraha, D., Wahlanto, P., Indriastuti, M., Ismail, R., & Himah, F. A. . (2022). Formulasi Dan Evaluasi Sediaan Gel Ekstrak Buah Pare (Momordica Charantia L.) Dengan Variasi Konsentrasi Carbopol 940. Pharmacy

Downloads

Published

2023-05-17

How to Cite

Risnawan, E., & Nugraha, D. (2023). Formulation and Evaluation of Catfish ( Calias Sp ) Albumin Extract Ointment with Variations of Basis. Ad-Dawaa : Journal of Pharmacy, 1(1), 1–9. https://doi.org/10.52221/dwj.v1i1.220