Formulation and Evaluation of Clove Flower Extract (Syzygium aromaticum L.) Toothpaste Aidie With Variations of NA CMC Concentration as a Binder

Authors

  • Sinta Herawayanti STIKes Muhammadiyah Ciamis
  • Marlina Indriastuti STIKes Muhammadiyah Ciamis

DOI:

https://doi.org/10.52221/mjmlt.v3i1.790

Keywords:

Toothpaste, Clove Flower Extract, Toothpaste Evaluation

Abstract

Background & Objective: Toothpaste is a semi-solid preparation that contains abrasives, cleansers, and additives to clean teeth without damaging oral tissues. Clove flower (Syzygium aromaticum L.) is known to contain eugenol, saponins, and flavonoids, which are analgesic. The purpose of this study was to make and evaluate toothpaste preparations from clove flower extract.

Method: The research was conducted experimentally with toothpaste formulation using variations in Na CMC concentration as a binder: 2%, 1%, and 0.5%. Evaluation included organoleptic test, homogeneity, pH, viscosity, spreadability, foam formation, and physical stability. Data were analyzed using SPSS.

Result: All formulas met the evaluation standards. Formula I was closest to the positive control in organoleptic, having an average viscosity of 9600 mPa.s and spreadability of 5.2 cm. Formula II showed the best pH with an average of 8.74. All three formulas produced foam well. Physical stability for 4 weeks showed that the texture and pH remained stable.

Conclusion: Na CMC affects the viscosity and spreadability of toothpaste preparations. Formulas with the right concentration of Na CMC can produce herbal toothpaste that is stable and meets quality requirements.

References

Andries, J. R., Gunawan, P. N., & Supit, A. (2014). UJI EFEK ANTI BAKTERI EKSTRAK BUNGA CENGKEH TERHADAP BAKTERI Streptococcus mutans SECARA IN VITRO. E-GIGI, 2(2). https://doi.org/10.35790/eg.2.2.2014.5763

Daud, N. S., Desi, S. A., & Ifaya, M. (2016). Formulasi Pasta Gigi Infusa Daun Jambu Biji (Psidium guajavaLinn.) Dengan Variasi Konsentrasi Na. CMC Sebagai Bahan Pengikat. Jurnal Ilmiah Ibnu Sina, 1(1), 42–49.

Forestryana, D., Surur Fahmi, M., & Novyra Putri, A. (2020). Pengaruh Jenis dan Konsentrasi Gelling Agent pada Karakteristik Formula Gel Antiseptik Ekstrak Etanol 70% Kulit Buah Pisang Ambon. Lumbung Farmasi: Jurnal Ilmu Kefarmasian, 1(2), 45. https://doi.org/10.31764/lf.v1i2.2303

Ilmiah, P., Qomariah, R. I. A. L., Farmasi, P. S., Farmasi, F., & Surakarta, U. M. (2017). Formulasi pasta gigi ekstrak etanol bunga turi (.

Indonesia, D. K. R. (2000). No Title. Farmakope Indonesia Edisi IV.

Makanan, B. P. O. dan. (2021). No Title. Pedoman Teknis Evaluasi Pasta Gigi.

Oliver, J. (2013). No Title. Perbedaan Penggunaan Bahan Pengikat Na CMC Dan HPMC Terhadap Sifat Fisik, Kimia Dan Uji Hedonik Sediaan Pasta Gigi Enzim Papain Pepaya (Carica Papaya L.), 53(9), 1689–1699.

Sayuti, N. A. (2015). Formulasi dan Uji Stabilitas Fisik Sediaan Gel Ekstrak Daun Ketepeng Cina (Cassia alata L.). Jurnal Kefarmasian Indonesia, 5(2), 74–82. https://doi.org/10.22435/jki.v5i2.4401.74-82

Susilowati, E. P., & Wahyuningsih, S. S. (2014). Optimasi Sediaan Salep yang Mengandung Eugenol dari Isolasi Minyak Cengkeh (Eugenia Caryophylatta Thunb.). IJMS-Indonesian Journal On Medical Science, 1(2), 29–34.

Syurgana, M. U., Febriana, L., & Ramadhan, A. M. (2017). Proceeding of the 6 th Mulawarman Pharmaceuticals Conferences FORMULASI PASTA GIGI DARI LIMBAH CANGKANG TELUR BEBEK. Mulawarman Pharmaceuticals Conferences , November, 7–8. https://doi.org/10.25026/mpc.v6i1.275

Ruhimat, U., Mutmainah, R. N., Ramdan, S. R. K., & Firdaus, N. R. (2024). Utilization of Purple Sweet Potato Juice As an Alternative Violet Crystal in Coloring Streptococcus sp Bacteria and Escherichia coli. JURNAL KESEHATAN STIKes MUHAMMADIYAH CIAMIS, 11(2), 149-156.

Triananda, A. L., & Wijaya, A. (2021). FORMULASI DAN UJI FISIK SEDIAAN GEL EKSTRAK DAUN PETAI CINA ( Leucaena leucocephala ( Lam .) De . Wit ) DENGAN BASIS HYDROXY PROPYL METHYL CELLULOSE ( HPMC ) FORMULATION AND PHYSICAL PROPERTIES TEST OF PETAI CINA ( Leucaena leucocephala ( Lam .) De . Wit . 29–36.

Warnida, H., Juliannor, A., & Sukawaty, Y. (2016). Formulation of Bawang Dayak (Eleutherine bulbosa (Mill.) Urb.) Extract into a Gel Toothpaste. Jurnal Sains Farmasi & Klinis, 3(1), 42–49. http://jsfkonline.org/index.php/jsfk/article/view/98

Winarno, F. G. (2004). No Title. Kimia Pangan Dan Gizi.

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Published

2025-04-21

How to Cite

Herawayanti, S. ., & Indriastuti, M. (2025). Formulation and Evaluation of Clove Flower Extract (Syzygium aromaticum L.) Toothpaste Aidie With Variations of NA CMC Concentration as a Binder. Mukhtabar : Journal of Medical Laboratory Technology, 3(1), 1–8. https://doi.org/10.52221/mjmlt.v3i1.790